Management of Focal Chondral Lesion in the Knee Joint
The Journal of Korean Knee Society
; : 185-196, 2011.
Article
in En
| WPRIM
| ID: wpr-759038
Responsible library:
WPRO
ABSTRACT
Articular cartilage does not contain vascular, nervous and lymphatic tissue and chondrocytes hardly participate in the healing or repair process of chondral tissue because of being surrounded by plenty of extracellular matrix. Therefore, the injury to articular cartilage frequently requires an operative treatment. The goal of surgical repair of articular cartilage is to regenerate nearly normal chondral tissue and prevent degenerative arthritis caused by the articular cartilage defect. Microfracture is a kind of cartilage repair procedure that makes a fibrin clot containing mesenchymal stem cells in the chondral lesion. Microfracture is a simple procedure but it has a disadvantage that the repaired tissue is fibrocartilage. Autologous chondrocyte implantation has an advantage that it implants fully differentiated chondrocytes to the lesion, which theoretically produces hyaline cartilage. Its disadvantages are that it is a two stage and a costly procedure. Osteochondral autograft transplantation is a one stage procedure and repairs the lesion with hyaline cartilage. But its limitation is the lack of donor site availability. Surgeons who understand the theoretical background, indications, surgical methods, rehabilitation, complications, and clinical course of cartilage repair procedures can achieve the goal of preventing degenerative arthritis.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Osteoarthritis
/
Tissue Donors
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Fibrin
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Cartilage
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Cartilage, Articular
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Chondrocytes
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Transplants
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Fibrocartilage
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Hyaline Cartilage
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Extracellular Matrix
Limits:
Humans
Language:
En
Journal:
The Journal of Korean Knee Society
Year:
2011
Document type:
Article