Psychiatric Symptoms after Taking Oseltamivir in a Child and Its Causality Assessment
Korean Journal of Clinical Pharmacy
; : 56-60, 2019.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-759606
Responsible library:
WPRO
ABSTRACT
Oseltamivir is an antiviral medication prescribed to prevent and treat influenza A and B. A case from a community pharmacy in Korea was reported for an adverse event associated with oseltamivir administration. A 20-month-old boy had psychiatric symptoms after receiving 2 doses of oseltamivir. Therefore, an evaluation of whether the psychiatric symptoms were caused by oseltamivir was required. To determine whether the adverse event resulted from the administrated medication or other factors, three tools were used the Naranjo scale, the Korean causality assessment algorithm (Ver.2), and the World Health Organization-Uppsala Monitoring Center (WHO-UMC) criteria. The psychiatric symptoms occurred after oseltamivir administration, and were attenuated after oseltamivir termination. A possible cause of the psychiatric symptoms is high fever, but information on the body temperature of the patient was not sufficient. Therefore, it was unclear whether there were other nonpharmacological causes of adverse drug reaction. For these reasons, in terms of causality, the results evaluated by the three tools represented, “possible”, “probable”, and “probable/likely”, respectively.
Full text:
Available
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.8 Achieve universal access to health
Database:
WPRIM (Western Pacific)
Main subject:
Pharmacies
/
Body Temperature
/
Global Health
/
Drug-Related Side Effects and Adverse Reactions
/
Influenza, Human
/
Oseltamivir
/
Fever
/
Korea
Type of study:
Diagnostic study
/
Etiology study
Limits:
Child
/
Humans
/
Infant
/
Male
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Clinical Pharmacy
Year:
2019
Document type:
Article