Prevalence and molecular characteristics of 16s rRNA methylase gene rmtB in amikacin resistant Escherichia coli isolated from South Korea / 대한수의학회지
Korean Journal of Veterinary Research
; : 157-160, 2019.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-760359
Responsible library:
WPRO
ABSTRACT
The production of rmtB-encoded 16S rRNA methylases has emerged as a novel mechanism promoting high-level resistance toward aminoglycosides in Gram-negative bacteria. Between 2015 and 2017, 636 distinct commensal Escherichia (E.) coli isolates were collected from different farms in South Korea to determine the prevalence and molecular characteristics of rmtB. The positive rates of rmtB between all the isolates and amikacin-resistant isolates were 1.1 and 100%, respectively. High-level aminoglycoside resistance could be transferred by conjugation from rmtB-positive donors to higher amikacin-resistance efficacies. This is the first report of 16S rRNA methylase-encoding genes in E. coli isolated from food-producing animals in Korea.
Full text:
Available
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Zoonoses
Database:
WPRIM (Western Pacific)
Main subject:
Tissue Donors
/
Amikacin
/
Prevalence
/
Agriculture
/
Escherichia
/
Escherichia coli
/
Gram-Negative Bacteria
/
Aminoglycosides
/
Korea
Type of study:
Prevalence study
/
Risk factors
Limits:
Animals
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Korean Journal of Veterinary Research
Year:
2019
Document type:
Article