Patchy echogenicity of the liver in patients with chronic hepatitis B does not indicate poorer elasticity
Ultrasonography
; : 327-335, 2019.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-761993
Responsible library:
WPRO
ABSTRACT
PURPOSE:
This study was conducted to investigate whether the presence of patchy echogenicity in the liver of patients with chronic hepatitis B (CHB) is predictive of liver stiffness.METHODS:
A total of 200 CHB patients with and without patchy echogenicity of the liver were assigned to two groups, with 100 patients in each group, and 32 of them underwent liver biopsy. Additionally, 80 healthy subjects, 100 inactive HBV carriers, and 100 patients with decompensated hepatic cirrhosis were assigned to the control groups. Laboratory tests and clinical data were collected, and shear wave velocity (SWV) of the liver was measured for all 480 subjects.RESULTS:
The median SWV in patients with a normal liver, inactive hepatitis B virus carriers, CHB patients with and without patchy echogenicity, and decompensated hepatic cirrhosis were 1.07 m/sec, 1.08 m/sec, 1.16 m/sec, 1.16 m/sec, and 2.02 m/sec, respectively; there was no significant difference in SWV values between CHB patients with patchy echogenicity and those without patchy echogenicity. Furthermore, among CHB patients with and without patchy echogenicity, no significant difference in SWV was found according to fibrosis stage.CONCLUSION:
The presence of patchy echogenicity of the liver does not indicate a higher degree of liver stiffness.
Full text:
Available
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.3: End transmission of communicable diseases
Database:
WPRIM (Western Pacific)
Main subject:
Biopsy
/
Fibrosis
/
Hepatitis B virus
/
Ultrasonography
/
Hepatitis B, Chronic
/
Elasticity
/
Healthy Volunteers
/
Hepatitis, Chronic
/
Liver
/
Liver Cirrhosis
Type of study:
Diagnostic study
Limits:
Humans
Language:
English
Journal:
Ultrasonography
Year:
2019
Document type:
Article