Trends in contralateral prophylactic mastectomy rate according to clinicopathologic and socioeconomic status
Annals of Surgical Treatment and Research
; : 113-118, 2019.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-762699
Responsible library:
WPRO
ABSTRACT
PURPOSE:
There has been an increasing trend in the use of contralateral prophylactic mastectomy (CPM) among women diagnosed with unilateral breast cancer or mutations in BRCA1 or BRCA2 to reduce the occurrence of contralateral breast cancer. This study aimed to examine trends in the CPM rate according to clinicopathologic and socioeconomic status at a single institution in Korea.METHODS:
This study included 128 patients with mutations in BRCA1 or BRCA2. Patients were divided into a CPM group (n = 8) and a non-CPM group (n = 120) between May 2013 and March 2016. The main outcome variables, including epidemiology, clinical features, socioeconomic status, and tumor characteristics, were analyzed.RESULTS:
A total of 8 CPMs were performed among 128 patients. All CPM patients were married. The proportion of professional working women was higher in the CPM group (P = 0.049). Most patients who underwent CPM graduated college, compared to less than a third of the non-CPM group (P = 0.013). The CPM group had a higher rate of visits to the Hereditary Breast and Ovarian Cancer (HBOC) clinic (P = 0.021). The risk-reducing salpingo-oophorectomy (RRSO) rate was significantly higher in the CPM group (P < 0.01).CONCLUSION:
CPM rates were significantly different according to socioeconomic status. The CPM rate tends to increase in highly educated and professional working women. The socioeconomic status of patients is an important factor in the decision to participate in the HBOC clinic and undergo CPM or RRSO.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Ovarian Neoplasms
/
Social Class
/
Women, Working
/
Breast
/
Breast Neoplasms
/
Epidemiology
/
Unilateral Breast Neoplasms
/
Korea
/
Mastectomy
Type of study:
Prognostic study
Aspects:
Social determinants of health
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Annals of Surgical Treatment and Research
Year:
2019
Document type:
Article