Variability of Platelet Reactivity on Antiplatelet Therapy in Neurointervention Procedure
Journal of Korean Neurosurgical Society
; : 3-9, 2019.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-765325
Responsible library:
WPRO
ABSTRACT
As more intracranial aneurysms and other cerebrovascular pathologies are treated with neurointervention procedure, thromboembolic events that frequently lead to serious neurological deficit or fatal outcomes are increasing. In order to prevent the thromboembolic events, antiplatelet therapy is used in most procedures including coil embolization, stenting, and flow diversion. However, because of variable individual pharmacodynamics responses to antiplatelet drugs, especially clopidogrel, it is difficult for clinicians to select the adequate antiplatelet regimen and its optimal dose. This article reviews the neurointervention literature related to antiplatelet therapy and suggests a strategy for tailoring antiplatelet therapy in individual patients undergoing neurointervention based on the results of platelet function testing.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Platelet Function Tests
/
Blood Platelets
/
Platelet Aggregation Inhibitors
/
Stents
/
Intracranial Aneurysm
/
Aspirin
/
Fatal Outcome
/
Embolization, Therapeutic
Limits:
Humans
Language:
English
Journal:
Journal of Korean Neurosurgical Society
Year:
2019
Document type:
Article