Estimating Influenza-associated Mortality in Korea: The 2009–2016 Seasons / 예방의학회지
Korean Journal of Preventive Medicine
; : 308-315, 2019.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-766151
Responsible library:
WPRO
ABSTRACT
OBJECTIVES:
Estimating influenza-associated mortality is important since seasonal influenza affects persons of all ages, causing severe illness or death. This study aimed to estimate influenza-associated mortality, considering both periodic changes and age-specific mortality by influenza subtypes.METHODS:
Using the Microdata Integrated Service from Statistics Korea, we collected weekly mortality data including cause of death. Laboratory surveillance data of respiratory viruses from 2009 to 2016 were obtained from the Korea Centers for Disease Control and Prevention. After adjusting for the annual age-specific population size, we used a negative binomial regression model by age group and influenza subtype.RESULTS:
Overall, 1 859 890 deaths were observed and the average rate of influenza virus positivity was 14.7% (standard deviation [SD], 5.8), with the following subtype distribution A(H1N1), 5.0% (SD, 5.8); A(H3N2), 4.4% (SD, 3.4); and B, 5.3% (SD, 3.7). As a result, among individuals under 65 years old, 6774 (0.51%) all-cause deaths, 2521 (3.05%) respiratory or circulatory deaths, and 1048 (18.23%) influenza or pneumonia deaths were estimated. Among those 65 years of age or older, 30 414 (2.27%) all-cause deaths, 16 411 (3.42%) respiratory or circulatory deaths, and 4906 (6.87%) influenza or pneumonia deaths were estimated. Influenza A(H3N2) virus was the major contributor to influenza-associated all-cause and respiratory or circulatory deaths in both age groups. However, influenza A(H1N1) virus–associated influenza or pneumonia deaths were more common in those under 65 years old.CONCLUSIONS:
Influenza-associated mortality was substantial during this period, especially in the elderly. By subtype, influenza A(H3N2) virus made the largest contribution to influenza-associated mortality.
Full text:
Available
Health context:
SDG3 - Health and Well-Being
/
SDG3 - Target 3.3 End transmission of communicable diseases
/
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Target 3.3: End transmission of communicable diseases
/
Pneumonia
/
Other Respiratory Diseases
Database:
WPRIM (Western Pacific)
Main subject:
Orthomyxoviridae
/
Pneumonia
/
Seasons
/
Mortality
/
Cause of Death
/
Population Density
/
Cost of Illness
/
Influenza, Human
/
Korea
Type of study:
Prognostic study
Limits:
Aged
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Korean Journal of Preventive Medicine
Year:
2019
Document type:
Article