Progress on the Study of PD-L1 Detection Methods in Non-small Cell Lung Cancer / 中国肺癌杂志
Chinese Journal of Lung Cancer
; (12): 40-44, 2019.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-772333
Responsible library:
WPRO
ABSTRACT
PD-1/PD-L1 inhibitors play an important role in the first-line and second-line treatment of non-small cell lung cancer (NSCLC), indicating a new treatment strategy of NSCLC. Completed clinical trials have shown that effective detection of PD-L1 expression is the key to the use of immunosuppressive agents. However, the gold standard for PD-L1 detection has still lacked. In recent years, immunohistochemistry (IHC) and enzyme-linked immunosorbent assay (ELISA) have been continuously innovated, which accounts for good prospect in PD-L1 detection. The research progress of PD-L1 detection methods in NSCLC is summarized in this review.
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Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Enzyme-Linked Immunosorbent Assay
/
Immunohistochemistry
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Biomarkers, Tumor
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Reproducibility of Results
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Sensitivity and Specificity
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Carcinoma, Non-Small-Cell Lung
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Diagnosis
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B7-H1 Antigen
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Lung Neoplasms
/
Metabolism
Type of study:
Diagnostic study
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Lung Cancer
Year:
2019
Document type:
Article