Meta Analysis of Risks of Cardiocerebral Vascular Events in Patients with Primary Biliary Cholangitis / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 457-463, 2019.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-776010
Responsible library:
WPRO
ABSTRACT
To systematically evaluate the risks of cardiocerebral vascular events in patients with primary biliary cholangitis(PBC). Methods We carried out a Meta analysis by RevMan 5.3 software to investigate literatureon the risk of cardiocerebral vascular events in patients with PBC and controls. Results Compared with non-PBC controls,PBC patients had significantly higher risk of coronary events(=1.56,=0.0002);however,the risk of cerebrovascular events showed no significant difference between these two groups(=1.01,=0.94).Subgroup analysis demonstrated a significantly lower risk of transient ischemic attack or carotid stenosis in PBC patients(=0.63,=0.03);however,there was no significant difference in the risk of stroke(=1.11,=0.40). Conclusion Patients with PBC have an increased risk of coronary events but may have a lower risk of transient ischemic attack or carotid stenosis.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Ischemic Attack, Transient
/
Cholangitis
/
Risk Factors
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Carotid Stenosis
/
Coronary Disease
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Stroke
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Liver Cirrhosis, Biliary
Type of study:
Etiology study
/
Risk factors
/
Systematic review
Limits:
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2019
Document type:
Article