Mechanism of action of microRNA in the regulation of hepatic ischemia-reperfusion injury / 临床肝胆病杂志
Journal of Clinical Hepatology
; (12): 1629-1631, 2019.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-779090
Responsible library:
WPRO
ABSTRACT
Hepatic ischemia-reperfusion injury is one of the most important factors affecting the prognosis of clinical hepatic surgery. Studies have shown that microRNAs can participate in the process of hepatic ischemia-reperfusion injury through multiple pathways. This article reviews the biosynthesis and function of microRNAs and the mechanisms of action of microRNAs in the regulation of hepatic ischemia-reperfusion injury through energy metabolism, apoptosis, autophagy, oxidative stress, and cellular inflammation. It is pointed out that the treatment targeting microRNAs has a promising future in the treatment of hepatic ischemia-reperfusion injury, and further studies are needed in the future.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of Clinical Hepatology
Year:
2019
Document type:
Article