Advances of antineoplastic agents based on mitochondrial targeting mechanism / 药学学报
Acta Pharmaceutica Sinica
; (12): 879-887, 2017.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-779670
Responsible library:
WPRO
ABSTRACT
Mitochondrion is an important organelle in cells and plays a crucial role in tumor development. Therefore, improvement of the targeting ability of anticancer drugs to mitochondria will increase the treatment efficacy for tumor and reduce the side effect on normal tissues. Here, research progresses in mitochondrial targeting have been reviewed in three aspects for tumors treatment the potential, permeability and translocase of mitochondrial membrane. The review provides a reference for the development of mitochondria targeted therapeutic systems.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2017
Document type:
Article