Short- and long-term outcomes of pancreaticoduodenectomy in elderly patients with periampullary cancer
Annals of Surgical Treatment and Research
; : 7-14, 2020.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-785428
Responsible library:
WPRO
ABSTRACT
PURPOSE:
Pancreaticoduodenectomy (PD) is recently performed in older cancer patients. The complication rate of PD is high. The present study was to compare the postoperative short- and long-term outcomes of PD in between older patients and younger patients.METHODS:
Between 2000 and 2014, patients who underwent PD due to periampullary cancers were enrolled. Patients aged 75 years or over were included in the older group.RESULTS:
Total 1,249 patients were enrolled in this study and 168 patients (13.5%) were included in the older group. Postoperative complication rates, duration of postoperative hospital stay, and 30-day mortality were comparable between the 2 groups, although the admission rate of intensive care unit postoperatively was higher in the older adult group (20.8% vs. 10.5%, P < 0.001). In terms of long-term outcomes, 5-year overall survival rate was lower in the older group (23.4% vs. 41.8%, P < 0.001), and 5-year cumulative recurrence rate was higher in the older group without statistical significance (63.9% vs. 57.9%, P = 0.095). However, there were no statistical differences of cumulative recurrence in pancreatic cancer patients (81.5% vs. 82.5%, P = 0.805).CONCLUSION:
PD for periampullary cancer is a safe and feasible treatment in the older patients. The treatment modality for obtaining better survival outcomes will be investigated.
Full text:
Available
Health context:
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Endocrine System Diseases
/
Pancreas Cancer
Database:
WPRIM (Western Pacific)
Main subject:
Pancreatic Neoplasms
/
Postoperative Complications
/
Recurrence
/
Geriatric Assessment
/
Survival Rate
/
Mortality
/
Pancreaticoduodenectomy
/
Intensive Care Units
/
Length of Stay
Type of study:
Prognostic study
Limits:
Adult
/
Aged
/
Humans
Language:
English
Journal:
Annals of Surgical Treatment and Research
Year:
2020
Document type:
Article