Dialysis modality-related disparities in sudden cardiac death: hemodialysis versus peritoneal dialysis
Kidney Research and Clinical Practice
; : 490-498, 2019.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-786197
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
Patients require risk stratification and preventive strategies for sudden cardiac death (SCD) based on the dialysis modality because the process of dialysis is a risk factor for SCD. This study aimed to compare the risk of SCD in patients undergoing hemodialysis (HD) versus peritoneal dialysis (PD).METHODS:
Patients on HD and PD were included in the end-stage renal disease registry of the Korean Society of Nephrology between 1985 and 2017. The incidence and associated factors of SCD were analyzed based on the dialysis modalityRESULTS:
Of 132,083 patients, 34,632 (26.2%) died during 94.8 ± 73.6 months of follow-up. In patients on HD and PD, 22.2% and 19.6% of total deaths were SCDs. In the propensity score-matched population, SCD accounted for 21.7% and 19.6% of total deaths in patients on HD and PD, respectively. HD was independently associated with SCD even after adjusting for age and significant comorbidities. Hypertension, coronary artery disease, and congestive heart failure, and age at the time of death < 65 years were independent risk factors for SCD in patients on HD but not in those on PD. Diabetes was significantly associated with SCD regardless of the dialysis modality.CONCLUSION:
Compared with patients on PD, Korean patients on HD have a higher risk of SCD, which is attributable to cardiac comorbidities.
Full text:
Available
Health context:
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Arterial Hypertension
/
Cardiovascular Disease
/
Chronic Kidney Disease
/
Ischemic Heart Disease
/
Other circulatory Diseases
/
Other Malignant Neoplasms
Database:
WPRIM (Western Pacific)
Main subject:
Coronary Artery Disease
/
Comorbidity
/
Incidence
/
Risk Factors
/
Follow-Up Studies
/
Renal Dialysis
/
Peritoneal Dialysis
/
Death, Sudden, Cardiac
/
Dialysis
/
Heart Failure
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Kidney Research and Clinical Practice
Year:
2019
Document type:
Article