Childhood Trauma and Treatment Implications in Major Depressive Disorder in South Korea: Comparison with Medical Outpatients and Two-Year Follow-Up / 우울ㆍ조울병
Mood and Emotion
; (2): 89-98, 2019.
Article
in En
| WPRIM
| ID: wpr-786420
Responsible library:
WPRO
ABSTRACT
BACKGROUND: Little is known about the specific types of childhood trauma and their relationship to treatment-related issues in major depressive disorder (MDD). This study examined trauma experiences and treatment-related variables in outpatients with MDD at a psychiatric department of a university hospital in Korea.METHODS: First, 75 outpatients with MDD were compared to medical outpatients without MDD matched by age, sex, income, and educational qualifications. Both groups completed the Life Stressor Checklist-Revised, which assesses comprehensive life events. Second, treatment-related variables and medication compliance measured by the Compliance Rating Scale were investigated for the two-year period after the initial assessment.RESULTS: The MDD group had experienced a significantly higher number of lifetime traumas than the control group (p=0.003), including more frequent witnessing of family violence (p<0.001), adulthood physical assault by a family member (p<0.001), and childhood emotional abuse (CEA) (p<0.001). CEA was associated with early onset of the first depressive episode and premature termination of pharmacotherapy; childhood physical neglect was associated with premature termination and less time in therapy.CONCLUSION: Our findings support the important influence of childhood emotional trauma and its relationship to treatment retention.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Outpatients
/
Patient Dropouts
/
Child Abuse
/
Follow-Up Studies
/
Domestic Violence
/
Compliance
/
Depressive Disorder, Major
/
Drug Therapy
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Medication Adherence
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Korea
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Child
/
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
Mood and Emotion
Year:
2019
Document type:
Article