Solid-phase synthesis of the antifungal tetrapeptide from the culture of penicilli-um canescens / 药学实践杂志
Journal of Pharmaceutical Practice
; (6): 342-343,378, 2014.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-790355
Responsible library:
WPRO
ABSTRACT
Objective To synthesize the antifungal tetrapetide by solid-phase synthesis method .Methods The solid-phase peptide synthesis was chosen for getting the desired target tetrapeptide and its structure was confirmed by MS and 1 H NMR.Results The synthesis of the D-Phe-Val-D-Val-Tyr-OH was realized with yield of 47%.Conclusion The synthetic method was feasible and practical.The desired target tetrapeptide could be used for screening of antifungal activity .
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Pharmaceutical Practice
Year:
2014
Document type:
Article