Research on quality control of Huoguwan / 药学实践杂志
Journal of Pharmaceutical Practice
; (6): 156-161, 2018.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-790854
Responsible library:
WPRO
ABSTRACT
Objective To establish the quality control method for Huoguwan.Methods TLC was applied to detect the component of Danshen,Dihuang,Danggui,Chuanxiong,Sanqi,Tubiechong,and Zhicaowu in this compound preparation. HPLC was used to measure the concentration of Renshenzaogan Rg 1,Rb1and Sanqizaogan R1.Unitary C18analytical column (4.6 mm×250 mm,5 μm)was used with acetonitrile-water as the mobile phase(Flow rate1.0 ml/min,column temperature30 ℃,wavelength203 nm).Results Each component showed distinct spots on TLC without interference.There are good linear relationship for Sanqizhaogan R1in the range of 39.92-399.2 μg/ml,Renshenzhaogan Rb1in 84.28-842.8 μg/ml and Renshenzhaogan Rg1in 135.86-1 358.6 μg/ml.The recovery was 102.35%,103.84% and 102.97% respectively.Conclusion The above described procedure was accurate and reproducible,which can be used as a method for the quality control of Huoguwan.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Pharmaceutical Practice
Year:
2018
Document type:
Article