Effect of flow rate and temperature of high flow nasal catheter on comfort of patients with acute hypoxic respiratory failure / 中国实用护理杂志

ABSTRACT

Objective@#To investigate the effect of high flow nasal catheter (HFNC) respiratory support flow and temperature on the comfort of patients with acute hypoxemic respiratory failure (AHRF), and the AHRF subgroup with severe hypoxemia (FiO2 ≥ 45%), improve HNFC flow to improve patient comfort.@*Methods@#A prospective, randomized, crossover study of 40 patients with AHRF who underwent HFNC respiratory support (PaO2/FiO2 ≤ 300 + pulmonary infiltration + exclusion of cardiogenic pulmonary edema) was performed to assess patient comfort changes in HFNC flow and temperature changes.@*Results@#When the HFNC flow rate was 30 L/min and 60 L/min, the patient′s comfort at 31 °C was significantly improved (P < 0.01), and the change in flow was not related to patient comfort. In the subgroup of patients with FiO2 ≥ 45%, lower temperature (31 °C) and higher HFNC flow (60 L/min) improved patient comfort (P < 0.01).@*Conclusion@#The temperature of HFNC respiratory support significantly affects the comfort of patients with AHFP. Patients with lower temperature are more comfortable, and comfort is not related to flow. For patients with severe hypoxemia (FiO2 ≥ 45%), high flow rates provide better comfort.