Advances in biomechanical study of sclera and scleral fibroblasts / 医用生物力学

ABSTRACT

Sclera plays an very important role in maintenance of eyeball structure and its functions. The biological and biomechanical properties of sclera is determined by the extra cellular matrix metabolism, the cytokine expression and its own biomechanical properties of scleral fibroblasts. Lots of biological and biomechanical changes in sclera and scleral fibroblasts are the concomitants in the process of myopic development and therapy. The biomechanical studies on sclera and scleral fibroblasts by Mechanics Biology coupling will enable to reveal the physiological function, pathological change and therapeutic mechanism of ocular organ and in this review, such biomechanical studies about sclera and scleral fibroblasts were summarized and discussed.