Protein expression and receptor binding specificity of porcine P19 rotavirus VP8* / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 89-92, 2018.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-805917
Responsible library:
WPRO
ABSTRACT
Objective@#To explore the receptor binding specificity of VP8* protein of porcine P[19] rotaviruses (RVs) with oligosaccharides.@*Methods@#The porcine P[19] VP8* protein was expressed and purified. The receptor binding specificity of P[19] VP8* was analyzed by oligosaccharide binding and saliva binding assay.@*Results@#The P[19] VP8* protein showed significant binding to mucin cores, especially mucin core 2.@*Conclusions@#Mucin core 2 may be a potential receptor for the porcine P[19] RV, which provides certain basis for the study of virus infection mechanism and RV surveillance.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2018
Document type:
Article