Synthesis of the related substances of deferasirox / 中国药科大学学报
Journal of China Pharmaceutical University
; (6): 288-290, 2016.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-811819
Responsible library:
WPRO
ABSTRACT
@#To perform the quality control of deferasirox and establish its quality criterion, three related substances which were determined by analyzing the synthetic route were synthesized, and their structures were confirmed by 1H NMR and MS. These substances were 2-(2-hydroxyphenyl)-4H-benzo[1, 3-e]oxazin-4-one(A), 2-hydroxy-N-(2-hydroxyben-zoyl)-benzamide(B), and methyl-4-[3, 5-bis(2-hydroxyphenyl)- 1H- [1, 2, 4]triazol-1-yl]-benzoate(C).
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of China Pharmaceutical University
Year:
2016
Document type:
Article