Non-alkaloid constituents of Vinca major / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 56-60, 2016.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-812450
Responsible library:
WPRO
ABSTRACT
The present study was designed to investigate the non-alkaloid compounds from the leaves and stems of Vinca major cultivated in Yunnan Province, China. The compounds were isolated using chromatographic techniques. The structures were elucidated by 1D- and 2D-NMR spectroscopic methods in combination with UV, IR, and MS analyses. The 1, 1-diphenyl-2-picrylhydrazyl (DPPH)-scavenging activity of Compounds 1-7 were evaluated. One new iridoid glycoside (compound 1), together with 11 known compounds, were isolated from Vinca major. Compounds 1, 5, and 6 showed moderate DPPH-scavenging activity, with IC50 values being 70.6, 32.8, and 62.2 μmol·L(-1), respectively. In conclusion, compound 1 is a newly identified iridoid glycoside with moderate antioxidant activity.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Chemistry
/
Plant Stems
/
Plant Leaves
/
Vinca
/
Iridoid Glycosides
/
Antioxidants
Language:
English
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Year:
2016
Document type:
Article