Identfication of new naphthalenones from Juglans mandshurica and evalution of their anticancer activities / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 707-710, 2015.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-812491
Responsible library:
WPRO
ABSTRACT
Two new naphthalenone compounds were isolated from green walnut husks of Juglans mandshurica and their structures were identified as 4-butoxybutoxy-5,8-dihydroxy-3,4-dihydro-2H-naphthalen-1-one (1), 4-ethoxyethoxy-5,8-dihydroxy-3,4-dihydro-2H-naphthalen-1-one (2). Compounds 1 and 2 were named as Juglanstetralone A (1) and Juglanstetralone B (2). Compound 1 showed more significant anti-tumor activity than 2 against gastric cancer BGC-823 cells, wih the IC50 of 125.89 (g(mL(-1).
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Stomach Neoplasms
/
Plant Extracts
/
Carcinoma
/
Chemistry
/
Juglans
/
Cell Line, Tumor
/
Therapeutic Uses
/
Drug Therapy
/
Phytotherapy
Limits:
Humans
Language:
English
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Year:
2015
Document type:
Article