Qilan Capsules plus androgen-deprivation therapy for Qi-deficiency blood-stasis type of prostate cancer after castration / 中华男科学杂志
National Journal of Andrology
; (12): 646-651, 2017.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-812901
Responsible library:
WPRO
ABSTRACT
Objective@#To observe the synergistic effect of Qilan Capsules in the treatment of the patient with Qi-deficiency blood-stasis type of prostate cancer receiving androgen-deprivation therapy after castration.@*METHODS@#This randomized controlled double-blind study included 246 cases of Qi-deficiency blood-stasis type of prostate cancer after castration, which were randomly divided into an experiment and a control group of equal number to be treated with Qilan Capsules + androgen-deprivation and placebo + androgen-deprivation, respectively. After 6 months of treatment, we compared the International Prostate Symptoms Scores (IPSS), TCM Symptoms Scores (TCMSS), maximal urine flow rate (Qmax), and the level of serum prostate-specific antigen (PSA) between the two groups of patients.@*RESULTS@#Statistically significant differences were observed between the experiment and control groups in the syndrome classification-based efficacy (87.7% vs 67.9%, P 0.05).@*CONCLUSIONS@#Qilan Capsules can significantly enhance the effect of androgen-deprivation therapy in the treatment of Qi-deficiency blood-stasis type of prostate cancer after castration though cannot obviously improve the PSA level.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Prostatic Neoplasms
/
Quality of Life
/
General Surgery
/
Blood
/
Capsules
/
Drugs, Chinese Herbal
/
Orchiectomy
/
Double-Blind Method
/
Treatment Outcome
/
Prostate-Specific Antigen
Type of study:
Controlled clinical trial
Aspects:
Patient-preference
Limits:
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2017
Document type:
Article