Characteristics and differential diagnosis of intestinal flora in Crohn's disease and intestinal tuberculosis / 中南大学学报(医学版)

ABSTRACT

OBJECTIVE@#To analyze the characteristics of intestinal flora in Crohn's disease (CD) and intestinal tuberculosis (ITb), and to find potential identification features to differentiate these 2 diseases.@*METHODS@#Fifteen CD patients, 23 ITb patients, and 21 healthy volunteers (controls) were enrolled from June 2007 to November 2009. Selective culturing was used for the enumeration of bacteria count.@*RESULTS@#The intestinal flora was mainly composed of Bifidobacteria, Bacteroids, Escherichia coli and Staphylococcus aureus both in CD and ITb patients. Lactobacillus and Bifidobacteria decreased obviously but Bacteroid increased in CD patients compared with the control (P0.05).@*CONCLUSION@#Intestinal flora disorder occurred in either CD or ITb patients. The alteration of Bacteroid and Escherichia coli can help differentiate the 2 diseases.