Clinical application of the 3-dimensional speckle tracking imaging in coronary artery disease / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 1060-1065, 2012.
Article
in Zh
| WPRIM
| ID: wpr-814753
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To observe the 3-dimensional speckle tracking imaging (3D-STI) in clinical diagnosis of coronary artery disease by quantitatively evaluating left ventricular segmental and global systolic function.@*METHODS@#According to the selective coronary artery angiography, 150 inpatients suspected of coronary artery disease were divided into 5 groups according to the distribution of the affected coronary arteries: a left anterior descending coronary artery group (LAD, n=46), a left circumflex coronary artery group (LCX, n=25), a right coronary artery group (RCA, n=23), a multivessel group (n=26), and a normal group (n=30). Gensini score was calculated according to coronary artery angiography. Conventional echocardiography was applied in each patient and wall motion score index (WMSI) was calculated. 3D-STI was applied in each patient to evaluate the segmental and global systolic function in the left ventricle.@*RESULTS@#Compared with the normal group, ejection fraction was decreased in the multi-vessel group alone (P<0.05). Peak systolic 3D strains in all segments were decreased in the multi-vessel group (P<0.01), while peak systolic 3D strains in the main blood-supply segments were decreased significantly in the rest of the groups (P<0.05). Global 3-dimensional strain (G3DS) was negatively correlated with Gensini score in patients with coronary artery disease (r= -0.76, P<0.01). Receiver operating characteristic curve analysis demonstrated that G3DS was more sensitive and accurate in clinical diagnosis of coronary artery disease.@*CONCLUSION@#3D-STI can quantitatively evaluate the segmental and global systolic function of the left ventricle, and reflect the extent of coronary artery stenosis in patients with coronary artery disease.
Full text:
1
Database:
WPRIM
Main subject:
Systole
/
Coronary Artery Disease
/
Echocardiography
/
ROC Curve
/
Coronary Angiography
/
Imaging, Three-Dimensional
/
Coronary Stenosis
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Diagnosis
/
Heart Ventricles
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Humans
Language:
Zh
Journal:
Journal of Central South University(Medical Sciences)
Year:
2012
Document type:
Article