Influential factors for theraputic effect of steroid on adult primary nephrotic syndrome / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 78-82, 2015.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-815211
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To determine the factors associated with the eff ect of steroid on adult primary nephrotic syndrome.@*METHODS@#The general information, laboratory examination and renal pathological type of 425 patients with primary nephrotic syndrome were retrospectively analyzed.@*RESULTS@#Th ere were significant differences in the response to steroid among the pathological types of minimal change disease, focal segmental glomerulosclerosis and IgA nephropathy. Th e patients in the age of 14-24 years old showed the strongest response to steroid (P0.05), while there was significant difference in urine protein in 24 hour quantitation in the non-steroid resistance group between pre- and post-treatment (P<0.05).@*CONCLUSION@#Pathological types and ages of the patients are related to the steroid curative effect. The decrease in IgA probably affects the effect of steroid on primary nephrotic syndrome.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Proteinuria
/
Steroids
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Glomerulosclerosis, Focal Segmental
/
Retrospective Studies
/
Urinalysis
/
Therapeutic Uses
/
Drug Therapy
/
Glomerulonephritis, IGA
/
Kidney
/
Nephrosis, Lipoid
Type of study:
Observational study
Limits:
Adolescent
/
Adult
/
Humans
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2015
Document type:
Article