DestructionandProtectionStrategyofBlood-brainBarrierDuringIschemicStroke / 中山大学学报(医学科学版)
Journal of Sun Yat-sen University(Medical Sciences)
; (6): 641-647, 2019.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-817676
Responsible library:
WPRO
ABSTRACT
@#Blood-brainbarrier（BBB），abarrierstructurebasedonbrainmicrovascularendothelialcells，playsan importantroleinmaintainingthehomeostaticmicroenvironmentofcentralnervoussystem（CNS）.Underthepathological conditionsofischemicstroke，localinflammationandchangesinthestatusandstructureofcellsleadtoBBBdisruption. AsaresultofBBBpermeabilityrising，variousbloodcomponents，especiallyactivatedinflammatorycellsorinflammatory factors，passthroughthedamagedBBBtoreachcerebralinfarctionareaandaggravatebraininjury.Thisarticlereviews themechanismofBBBdisruptionbythefunctionofactivatedcellsclusteredininfarctionareaafterischemicstrokeand brieflysummarizesourteam′scurrentworkonrepairingBBBinjuries.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Sun Yat-sen University(Medical Sciences)
Year:
2019
Document type:
Article
