Recent advances of exosome in autoimmune diseases / 医学研究生学报

ABSTRACT

Exosomes are multivesicular bodies ( 70120nm), and can be released by any type of cells after fusion with cell membranes. Exosomes mediate intercellular communication via transport proteins and nucleic acids, participating in a variety of physiological and pathological processes. According to the originated cells and target cells, exosomes play an important role in immunoregulation, serve as a biomarker for disease, a carrier for drug delivery,target of the pathogenesis of autoimmune diseases and immunotherapy. In this review, we will summarize current research advances of exosomes in immunoregulation, pathogenesis, diagnosis and therapeutics of autoimmune diseases.