Evaluation of the antimalarial potential of Icacina senegalensis Juss (Icacinaceae)
Asian Pacific Journal of Tropical Medicine
; (12): S469-72, 2014.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-820178
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To evaluate in vivo antimalarial activity of methanol leaf extract of Icacina senegalensis.@*METHODS@#The extract was investigated for activity against early and established malaria infections using Swiss albino mice infected with Plasmodium berghei at dose levels of 25, 50 and 100 mg/kg. Chloroquine (10 mg/kg) was used as positive control.@*RESULTS@#A dose dependent chemo-suppression of the parasites was observed at different dose levels of the extract tested with a considerable mean survival time.@*CONCLUSIONS@#The results support further investigation on components of traditional medicines as potential new antimalarial agents.
Full text:
Available
Health context:
Neglected Diseases
Health problem:
Malaria
Database:
WPRIM (Western Pacific)
Language:
English
Journal:
Asian Pacific Journal of Tropical Medicine
Year:
2014
Document type:
Article