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Cohort study on the relationship between women’s pre-pregnancy age, alanine aminotransferase, blood glucose level and premature birth / 公共卫生与预防医学
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-823144
Responsible library: WPRO
ABSTRACT
Objective  To investigate the effect of pre-pregnancy age, alanine aminotransferase (ALT), blood glucose (GLU) level on premature birth. Methods Based on the free pre-marital health check-ups and pre-pregnancy eugenic health check-ups in Dongguan, the examination results of the subjects were obtained and the pregnancy outcomes were followed up. Logistic regression models were used to analyze the relationship between women’s pre-pregnancy age, ALT, and GLU levels and the incidence of premature birth. Results A total of 18 150 subjects were included in this study, and the overall incidence of premature birth was 6.06% (1,099/18,150). The women’s pre-pregnancy age 30 to 34 (RR=1.26, 95% CI1.07~1.48), age>34 (RR=1.82, 95% CI1.52~2.18), ALT≥40 U/L (RR=1.40, 95% CI 1.09~1.80) and GLU>6.1 mmol/L(RR=1.74, 95% CI 1.01~2.97) were the influencing factors of premature birth. Conclusion Older women, abnormal serum alanine aminotransferase level and hyperglycemia had an impact on the occurrence of premature birth, which has important guiding significance for health education of eugenics before pregnancy.

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Database: WPRIM (Western Pacific) Type of study: Etiology study / Observational study / Prognostic study Language: Chinese Journal: Journal of Public Health and Preventive Medicine Year: 2020 Document type: Article
Search on Google
Database: WPRIM (Western Pacific) Type of study: Etiology study / Observational study / Prognostic study Language: Chinese Journal: Journal of Public Health and Preventive Medicine Year: 2020 Document type: Article
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