Gastric IgG4-related disease presenting as a mass lesion and masquerading as a gastrointestinal stromal tumor
Journal of Pathology and Translational Medicine
; : 258-262, 2020.
Article
| WPRIM (Western Pacific)
| ID: wpr-834563
Responsible library:
WPRO
ABSTRACT
IgG4-related disease of the stomach is a rare disorder, and only a few cases have been reported. We present two cases that were identified over a 2-month period in our center. Two male patients aged 52 and 48 years presented with mass lesion in the stomach, which were clinically thought to be gastrointestinal stromal tumor, and they underwent excision of the lesion. Microscopic examination revealed marked fibrosis, which was storiform in one case, associated with diffuse lymphoplasmacytic infiltration and an increase in IgG4-positive plasma cells on immunohistochemistry. Serum IgG4 level was markedly elevated. Although rare, IgG4-related disease should be considered in the differential diagnosis of gastric submucosal mass lesions.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Journal:
Journal of Pathology and Translational Medicine
Year:
2020
Document type:
Article