Implications of specific gene expression patterns in enamel knot in tooth development
International Journal of Oral Biology
; : 25-31, 2020.
Article
| WPRIM (Western Pacific)
| ID: wpr-835485
Responsible library:
WPRO
ABSTRACT
Enamel knot (EK)—a signaling center—refers to a transient morphological structure comprising epithelial tissue. EK is believed to regulate tooth development in early organogenesis without its own cellular alterations, including proliferation and differentiation. EKs show a very simple but conserved structure and share functions with teeth of recently evolved vertebrates, suggesting conserved signaling in certain organs, such as functional teeth, through the course of evolution. In this study, we examined the expression patterns of key EK-specific genes including Dusp26 , Fat4, Meis2, Sln , and Zpld1 during mice embryogenesis. Expression patterns of these genes may reveal putative differentiation mechanisms underlying tooth morphogenesis.
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Database:
WPRIM (Western Pacific)
Journal:
International Journal of Oral Biology
Year:
2020
Document type:
Article