Phenolic constituents of Pumbago zeylanica and their anti-oxidative effects / 中草药
Chinese Traditional and Herbal Drugs
; (24): 5419-5423, 2019.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-850694
Responsible library:
WPRO
ABSTRACT
Objective:
To investigate the phenolic compounds from Plumbago zeylanica and their anti-oxidant activities.Methods:
The phenolic compounds and their analogues were isolated and purified by silica gel column chromatography, semi-preparative HPLC, and HPLC. Their structures were identified by spectroscopy data. The isolated compounds were tested for anti-oxidant activity by ABTS assay.Results:
Twelve phenolic compounds were obtained and identified as (±)-5,5’-dimethoxyl ariciresionl 4’-O-β-D-glucopyranoside (1), tracheloside (2), quercetin-3-O-β-D-galactoside (3), quercetin-3-O-β-D-glucopyranoside (4), quercetin (5), quercetin 3-O-α-L-rhamnoside (6), kaempferol-3-O-α-L-rhamnoside (7), apigenin-6-C-β-D-glucopyranoside (8), luteolin 6-C-β- glucopyranoside (9), polybotrin (10), 3-O-(β-D-glucopyranosyl)-1-(3’,5’-dimethoxy-4’-hydroxyphenyl)-1-propanone (11), and (2E,4E,1’R,3’S,5’R,8’S)-dihydrophaseic acid-3’-O-β-D-glucopyranoside (12). The anti-oxidant activity experiment showed that compounds 3-9 displayed significant anti-oxidative activities.Conclusion:
All of the twelve phenolic compounds are isolated from this plant for the first time. The isolated flavones 3-9 displayed significant anti-oxidative activities.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2019
Document type:
Article