Optimization of test solutions preparation of Panax notoginseng in Chinese Pharmacopoeia by Box-Behnken response surface methodology / 中草药
Chinese Traditional and Herbal Drugs
; (24): 4145-4151, 2019.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-850885
Responsible library:
WPRO
ABSTRACT
Objective:
To study and optimize the preparation method of test solution from Panax notoginseng.Methods:
The effects of extraction solvent, liquid-material ratio and extraction temperature on the optimization of the preparation method of test solution of notoginsenoside and ginsenosides in P. notoginseng were investigated by Box-Behnken response surface methology. The content of notoginsenoside R1, ginsenoside Rg1, and ginsenoside Rb1 was simultaneously determined by HPLC.Results:
The optimum method was as follow 75% methanol was used for once reflux extraction, the ratio of liquid-material ratio was 140, the extraction temperature was 100 ℃.Conclusion:
The optimum preparation of test solution is simple and feasible, and the extraction rate of components is high, which provides a reference for the preparation of test solution from P. notoginseng.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2019
Document type:
Article