Chemical constituents from Spiraea salicifolia / 中草药
Chinese Traditional and Herbal Drugs
; (24): 2806-2811, 2016.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-853328
Responsible library:
WPRO
ABSTRACT
Objective:
To investigate the chemical constituents from the ethanol extract of Spiraea salicifolia.Methods:
The compounds were isolated and purified by chromatography on silica gel, ODS, and preparative HPLC methods. Their structures were elucidated on the basis of chemical and spectral data.Results:
Twelve compounds were isolated and identified as 7S,8R-3,5- dimethoxy-4',7-epoxy-8,5'-neolignan-3',4,9,9'-tetraol (1, salicifoneoliganol), 3β-acetylursolic acid methyl ester (2), 3β-acetyloleanolic acid methyl ester (3), lupeol (4), β-amyrin (5), (7R,8S)-5-methoxydiyhdrodehydroconiferyl alcohol (6), 8-hydroxy-7'-epipinoresinol (7), 8-hydroxypinoresinol (8), fraxiresinol (9), (+)-africannal (10), (+)-lyoniresinol (11), and 5-methoxy-(+)-isolariciresinol (12).Conclusion:
Compound 1 is a new lignan named salicifoneoliganol. Compounds 6 and 7 are isolated from the plants of Spiraea L. for the first time, and compounds 4, 5, and 8-12 are firstly obtained from this plant. Compounds 2 and 3 are artifacts of isolation from ursolic acid and loleanolic acid.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2016
Document type:
Article