Analysis of trace elements and heavy metals in Jiuwei Xifeng Granules by ICP-MS / 中草药

ABSTRACT

Objective:To establish a method for the simultaneous analysis of 25 trace elements and heavy metals in Jiuwei Xifeng Granules, including Li, Mg, Cd, Sn, Al, Mn, Fe, Ti, V, Co, Zn, Ga, Cr, Ni, Tl, Pb, Cu, As, Be, B, Sb, Ba, Sr, Hg, and Bi. Methods:The samples, digested via microwave, calibrated by internal standard elements, such as Ge and In, with bush branches and leaves as the controlled reference standard, were inlet into ICP-MS to analyze the contents of the 25 trace elements and heavy metals. Results:The detection limits of the 25 elements were in the range of 0.009-16.051 μg/L. The 25 trace elements and heavy metals showed the good linearity in the selected concentration ranges (R2 ≥ 0.999 2), with the average recovery from 70.75% to 107.66%, while their RSD was below ≤ 6.44%. Cr, Sn, Hg, and Pb were not detected in the six batches of samples, and the contents of Tl, Cd, As, and Cu were lower or not detected. Cd ≤ 0.011 μg/g, Cu ≤ 0.373 μg/g, Tl ≤ 0.021 μg/g, As ≤ 0.571 μg/g. Conclusion:The method is simple, rapid, and accurate, and can be used for the quality control of trace elements and heavy metals in Jiuwei-xifeng Granules.