Chemical constituents from Actinostemma lobatum (I) / 中草药

ABSTRACT

Objective: To study the chemical constituents from the whole plant of Actinostemma lobatum. Methods: The compounds were isolated and purified by various column chromatographies. Their structures were elucidated by means of chemical evidences and spectral analyses (MS, 1H-NMR, and 13C-NMR). Results: Sixteen compounds were isolated and identified as actinostemmoside A (1), actinostemmoside C (2), actinostemmoside D (3), actinostemmoside E (4), cucurbitacin E (5), β-sitosterol (6), daucosterol (7), α-spinasterol (8), α-spinasterol-3-O-β-D-glucopyranoside (9), 22, 23-dehydroxy-α-chondrillasterone (10), quercetin (11), kaempferol (12), rutin (13), quercitrin (14), kaempferol-3-O-α-L-rhamnopyranosyl (1→6)-β-D-glucoypyranoside (15), and isoquercitrin (16). Conclusion: Compounds 5-10 are obtained from this genus for the first time.