Determination of costunolide and dehydrocostuslactone in Liuwei Muxiang Capsules by HPLC / 中草药
Chinese Traditional and Herbal Drugs
; (24): 2349-2351, 2014.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-854843
Responsible library:
WPRO
ABSTRACT
Objective:
To establish an HPLC method for the determination of costunolide and dehydrocostuslactone in Liuwei Muxiang Capsules.Methods:
The determination was performed on VP-ODS (250 mm × 4.6 mm, 5 μm) with column temperature set at 25℃. The mobile phase consisted of methanol-0.4% phosphoric acid water (72∶28) at a flow rate of 1.0 mL/min. The detection wavelength was set at 225 nm.Results:
The linear range of costunolide and dehydrocostuslactone was 203.12-2 031.20 ng and 207.84-2 078.40 ng (r = 0.999 9), with average recovery at 101.1% and 101.2%, RSD = 0.48% and 0.73% (n = 6).Conclusion:
The method proved is simple, accurate, reproducible, and specific, and it can be used for the quality control and evaluation of Liuwei Muxiang Capsules.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2014
Document type:
Article