Purification technology of salidroside by microporous adsorption resin / 中草药

ABSTRACT

Objective: To optimize the purification technology of salidroside with macroporous adsorption resin. Methods: The absorption and elution conditions of salidroside purificatin by various macroporous adsorption resins were investigated with the content of salidroside as index. Results: SP-825 type macroporous adsorption resin was the best choice for the purification of salidroside. The optimized parameters were as follows: the content of salidroside at 1.713-2.570 g/mL, eluting solvent of 10% aqueous ethanol, volume flow at 2 BV/h, and eluant volume at 30 BV. Conclusion: SP-825 type macroporous adsorption resin could significantly increase the purity of salidroside with the advantage of high absorption, high elution rate, low cost, environment friendly, and being applicable for the production in large scale.