Progress of screening methods in vitro for HIV-1 capsid protein inhibitors / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 473-477, 2019.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-857351
Responsible library:
WPRO
ABSTRACT
Human immunodeficiency virus type 1 (HIV-1) infection is highly dependent on its conical fullerene capsid, which is composed of approximately 1 500 capsid proteins. In recent years, capsid protein has been recognized as an ideal target for design and screening drugs for AIDS therapy. Screening methods are the key to develop HIV-1 capsid inhibitors. A variety of screening approaches for HIV-1 capsid protein inhibitor, which have been reported in the literature are reviewed in the article.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
/
Screening study
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
2019
Document type:
Article