Promising Novel Applications of Heparin / 中国药学杂志
Chinese Pharmaceutical Journal
; (24): 1831-1839, 2019.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-857849
Responsible library:
WPRO
ABSTRACT
Heparin has been used as first-line anticoagulant clinically for 80 years. Heparin mainly exerts its anticoagulant activity through interaction with ATIII. It has been found there are more than one hundred heparin-dependent functional proteins which demonstrates promising novel application beyond anticoagulant, such as anti-tumor, anti-malaria anti-inflammation, anti-viral, anti-malaria anti-anemia, etc. Heparin is also hopeful to be used as tool for drug delivery vehicle and functionalized implants material. In addition, heparin oligosaccharides are expected to be produced by chemical/enzymatic and bioengineering synthesis. Above mentioned new developments of heparin are covered in this review.
Full text:
Available
Health context:
Neglected Diseases
Health problem:
Malaria
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
2019
Document type:
Article