Chemical Constituents from the Root Bark of Celastrus monospermus / 中国药学杂志
Chinese Pharmaceutical Journal
; (24): 1265-1272, 2018.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-858252
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
To study the chemical constituents from the root bark of Celastrus monospermus Roxb.METHODS:
The compounds were isolate and purified by repeated column chromatography on silica gel, ODS and Sephadex LH-20, and the chemical structures of compounds were determined by spectral data analyses.RESULTS:
Twenty-three compounds were isolated from this plant, which were identified as β-sitosterol palmitate (1), friedelan-3-one (2), 3β-hydroxyolean-12-en (3), 3β-hydroxylcholest-5,22-dien (4), β-sitosterol (5), 3,22-dioxo-20-taraxastene (6), 3,12-dioxofriedelane (7), 3-oxo-28-hydroxyfriedelane (8), 3-oxo-11β-hydroxyfriedelane (9), 3-oxo-12α-hydroxyfriedelane (10), pristimerin(11), 3-oxo-30-hydroxyfriedelane (12), 3-oxo-29-friedelanoic acid (13), salaspermic acid (14), celastrol (15), 3β, 21β-dihydroxy-30-nor-friedelan-20(29)-en-27-oic acid (16), 3β, 22α-dihydroxy-olean-12-en-29-oic acid (17), wilforol A (18), orthosphenic acid (19), p-hydroxybenzoic acid (20), 3-oxo-2β-hydroxyfriedelan-29-oic acid (21), 21-oxo-2α,3α,22β-trihydroxy-29-nor-friedelan-24,2β-lactone (22)and daucosterol (23).CONCLUSION:
Compounds 1,6, 13-14,16-22 are obtained from this plant for the first time, and compounds 16, 20-22 are isolated from the genus Celastrus for the first time.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
2018
Document type:
Article