Sulfanilamide desensitization treatment for systemic lupus erythematosus complicated with Pneumocystis pneumonia: a case report and case analysis / 中国药学杂志

ABSTRACT

OBJECTIVE: To report the clinical manifestations of one case systemic lupus erythematosus (SLE) complicated with Pneumocystis pneumonia(PCP), and the process that in accordance with the treatment guidelines of the patients who had a history of sulfa allergy in patients with sulfa desensitization program treatment. METHODS: Involved in the discussion of treatment of a patient in our hospitals intensive care unit who has systemic lupus erythematosus(SLE) complicated with Pneumocystis pneumonia(PCP) and history of sulfur allergy, and analyze the clinical data of the patient retrospectively. RESULTS: The middle-aged women suffering from systemic lupus erythematosus (systemic lupus erythematosus; SLE) combined Pneumocystis pneumonia (Pneumocystis pneumonia, PCP) infection. Due to her history of sulfa drug allergies, antibiotics and sulfa desensitization treatment were given. Symptoms were eased sputum smear PCP (negative). CONCLUSION: The infection is generally the main life-threatening reason to patients with autoimmune disease in clinical, taking a comprehensive treatment is a necessary measure for patients with SLE combined PCP for the patients who are allergic to Sulfa drugs with contraindications or undesirable effects using alternative drug. Desensitization treatment may be one of the choices for these patients. Copyright 2012 by the Chinese Pharmaceutical Association.