Mechanism study of PD-1/PD-L1 in tumor and its value of diagnosis and treatment of thyroid cancer / 国际肿瘤学杂志
Journal of International Oncology
; (12): 39-42, 2020.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-863431
Responsible library:
WPRO
ABSTRACT
Programmed death-1 (PD-1) and programmed death ligand-1 (PD-L1) are involved in the regulation of immune checkpoints and are closely related to the occurrence and development of tumors. In thyroid cancer, an increase in PD-L1 expression and an increase in PD-1 positive T cells may be predictive of higher invasiveness and a greater risk of recurrence. Anti-PD-1/PD-L1 therapy has had significant effects in many tumors, but the efficacy in thyroid cancer is still relatively limited, which also requires finding biomarkers those can better predict the efficacy. Further understanding of the mechanism of PD-1/PD-L1, the current research status in thyroid cancer, and biomarkers related to its efficacy may provide new treatment methods and ideas for patients with thyroid cancer.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
/
Prognostic study
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2020
Document type:
Article