Clinical application of dexmedetomidine in pediatrics / 中国小儿急救医学

ABSTRACT

Dexmedetomidine(DEX) is a new type of highly selective α 2 adrenergic receptor agonist with multiple effects, such as sedation, analgesic, anti-anxiety and inhibition of sympathetic nervous system activity.DEX is usually used as an anesthetic adjuvant and as an sedative and analgesic in PICU, also possessing effects of preventing and treating emergence agitation, counteracting postoperative shivering and organ protection.This paper summarized the clinical application of DEX in pediatric field.