Current status and progress of drug therapy for pulmonary hypertension / 中国基层医药

ABSTRACT

Pulmonary arterial hypertension(PAH) leads to increased pulmonary artery pressure, pulmonary vasoconstriction, thickening of vascular wall, malignant proliferation of smooth muscle and endothelial cells, pulmonary artery occlusion and other pathological changes, which ultimately lead to right heart failure.With the advance of basic and clinical research of PAH, new progress has been made in the treatment of PAH in recent years, which improves the prognosis of patients.This article reviews the progress of drug therapy for PAH.