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Timing of radical surgery in patients with postoperative incidentally discovered gallbladder cancer / 中华肝胆外科杂志
Article in Zh | WPRIM | ID: wpr-868774
Responsible library: WPRO
ABSTRACT
Objective To compare the tumor characteristics and survival between postoperative incidentally discovered gallbladder cancer (ID-GBC) and preoperatively suspected gallbladder cancer (PS-GBC).Methods The data of 276 GBC patients who underwent surgical resection with curative intent between January 2004 and December 2014 at the Eastern Hepatobiliary Surgery Hospital were retrospectively analyzed.Results The 1-,3-,and 5-year cumulative survival rates of the ID-GBC group (88.8%,52.2%,and 33.0%,respectively) were significantly better than those in the PS-GBC group (57.5%,25.7%,and 16.6%,P < 0.05).In the ID-GBC group,multivariate analysis revealed that T staging,hepatic invasion and time interval from cholecystectomy to re-operation were independent prognostic factors.The overall survival (OS) in the group with the time interval within 2 weeks was significantly better than those in the other two groups (both P < 0.05).However,there were no significant differences in OS between the groups with the time interval of 2 weeks to 1 month and more than 1 month (P > 0.05).Conclusions Postoperative ID-GBC had significantly better survival outcomes than PS-GBC.Reoperation within two weeks in patients with ID-GBC is a good strategy.
Key words
Full text: 1 Database: WPRIM Type of study: Prognostic_studies Language: Zh Journal: Chinese Journal of Hepatobiliary Surgery Year: 2020 Document type: Article
Full text: 1 Database: WPRIM Type of study: Prognostic_studies Language: Zh Journal: Chinese Journal of Hepatobiliary Surgery Year: 2020 Document type: Article