An FT 3/FT 4 ratio greater than 0.4 is helpful in differentiating Graves′ disease from subacute thyroiditis / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12): 794-798, 2020.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-870093
Responsible library:
WPRO
ABSTRACT
Objective:
To search for the clinical indicators in differentiating Graves′ disease from subacute thyroiditis (SAT).Methods:
Retrospective analysis was performed on thyroid function measurement of 265 cases of newly diagnosed Graves′ disease, 76 cases of SAT with thyrotoxicosis, 100 cases of non-toxic thyroid nodules, 105 cases of autoimmune thyroid diseases with normal thyroid function, and 151 cases of outpatients with normal thyroid function and without thyroid diseases.Results:
Free triiodothyronine(FT 3)/free thyroxine(FT 4) ratio of Graves′ disease patients was significantly higher than that of SAT patients with thyrotoxicosis (0.65±0.29 vs 0.32±0.75, P<0.05). Receiver operating characteristic curve(ROC curve) analysis of FT 3/FT 4 ratio between Graves′ disease group and SAT group showed that FT 3/FT 4 ratio greater than 0.4 with a sensitivity of 98.11% and a specificity of 83.81% for diagnosis of Graves′ disease.Conclusion:
FT 3/FT 4 ratio greater than 0.4 is helpful for differentiating Graves′ disease from subacute thyroiditis with thyrotoxicosis.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2020
Document type:
Article