Gastrointestinal lipolysis and trans-epithelial transport of SMEDDS

Fei XIA; Zhongjian CHEN; Quangang ZHU; Jianping QI; Xiaochun DONG; Weili ZHAO; Wei WU; Yi LU

Fei XIA; Zhongjian CHEN; Quangang ZHU; Jianping QI; Xiaochun DONG; Weili ZHAO; Wei WU; Yi LU.

Acta Pharmaceutica Sinica B ; (6): 1010-1020, 2021.

Article in English | WPRIM (Western Pacific) | ID: wpr-881181

Responsible library: WPRO

ABSTRACT

ABSTRACT

Self-microemulsifying drug delivery systems (SMEDDSs) have recently returned to the limelight of academia and industry due to their enormous potential in oral delivery of biomacromolecules. However, information on gastrointestinal lipolysis and trans-epithelial transport of SMEDDS is rare. Aggregation-caused quenching (ACQ) fluorescent probes are utilized to visualize the

Absorption; Aggregation-caused quenching; Caco-2; In vivo fate; Lipolysis; Lymph; SMEDDS; Trans-epithelial transport

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Full text: Available Database: WPRIM (Western Pacific) Language: English Journal: Acta Pharmaceutica Sinica B Year: 2021 Document type: Article

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Full text: Available Database: WPRIM (Western Pacific) Language: English Journal: Acta Pharmaceutica Sinica B Year: 2021 Document type: Article