Advances of motor unit number estimation and motor unit number index in amyotrophic lateral sclerosis / 中华神经科杂志
Chinese Journal of Neurology
; (12): 290-296, 2021.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-885419
Responsible library:
WPRO
ABSTRACT
Amyotrophic lateral sclerosis (ALS) is a rapid progressive neurodegenerative disease, characterized by the degeneration of both upper and lower motor neurons. The progressive motor unit loss due to lower motor neuron damage is one of the most important pathological process in ALS. However, there are lack of specific biomarkers for early diagnosis and progression monitoring of ALS. The relevant electrophysiologic techniques which quantify the number of motor unit have been developed rapidly in recent years. Among them, the motor unit number estimation (MUNE) and the motor unit number index (MUNIX) have been widely applied to quantify motor unit number loss in ALS. The most recent advances of MUNE and MUNIX in ALS were reviewed.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Screening study
Language:
Chinese
Journal:
Chinese Journal of Neurology
Year:
2021
Document type:
Article